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Pet Bucket Blog

June 2019

How does Nexgard work?

 by ben on 21 Jun 2019 |
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With zero hassle, each beef-flavored tasty Nexgard chew provides a full month of protection from biting pests. Made by the same company that created Frontline, Nexgard marks an innovation in flea and tick relief. Each beef-flavored, chewable treat packs a full month of protection from biting parasites, arming your do against harmful diseases, allergic reactions, and the notoriously difficult to destroy paralysis tick. Nexgard is effective in the fight against fleas and ticks thanks to its active ingredient, Afoxolaner. An insecticide and acaricide that attacks the central nervous system of invertebrates, Afoxolanerstarts to work fast to kill fleas within four hours of ingestion and continues working to provide a full month of relief from fleas and ticks. It works by targeting invertebrates’ nervous systems, rather than mammals’, making Nexgarddeadly to parasites, but safe for use on pets. Unlike other flea and tick medications, which work by entering the tissue under your dog’s skin, Nexgard enters the bloodstream directly to target pests as they bite. Afoxolaner works by selectively binding to certain pathways in invertebrates’ nervous systems. The first, known as GABA-gated (gamma-aminobutyric acid) channels, play a role in calming nerve transmissions and create an overall relaxation effect in the body. Afoxolaner disrupts these channels, causing spikes in nerve transmissions in fleas and ticks. At the same time, Afoxolaner bonds to glutamate-gated chloride channels, which help send nerve signals to other cells. By bonding with these channels, it increases nerve impulse transmissions. Together, these contribute to hyperexcitation of parasites’ nervous systems, creating an uncontrollable activity that is fatal to fleas and ticks. Because invertebrates’ nervous systems are not the same as mammals, clinical trials have found Nexgard to be safe for use in pets. Side effects observed in less than five percent of dogs tested included including vomiting, diarrhea, and dry skin—all symptoms of unrelated to Fido’s nervous system. However, if your pet has a history of epilepsy or a similar seizure disorder, talk to your veterinarian before giving him Nexgard. Nexgard has been tested and approved for use in puppies as young as eight weeks old and dogs over 4 pounds. The chews are also safe to give dogs currently taking other medications and are available in multiple doses for dogs of every size. Because it is delivered internally, Nexgard is effective for use on pets that swim and are washed regularly, saving you the hassle of messy topical treatments. Nexgard has not been evaluated for use in breeding pets, however, and should not be given to pregnant, nursing or breeding dogs. Discuss Nexgard for dogs with your veterinarian to provide your pet with powerful relief from fleas and ticks in one tasty, monthly chew.

How to treat dermatitis in cats

 by ben on 11 Jun 2019 |
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Fleas are the most common cause behind feline dermatitis, but your pet’s diet or environmental factors can also inflame his skin. If you’ve noticed your cat has been itching or licking a lot lately or have seen scabs on your pet, chances are he has dermatitis. It’s the general term for inflammation of the skin, and the source behind animals’ itchy, raw or red skin, as well as bald patches. Left untreated, this uncomfortable condition can lead to serious infections due to constant scratching of the affected area. Fortunately, you can treat dermatitis by addressing its root cause. In cases of moderate to severe dermatitis, pet owners willnoticebumps, scabs, crusting, cuts, redness or bald patches on their cats’ skin. More often, however, pets display nooutward signs of this condition. That means you need to pay close attention to your companion’s behaviorin order to spot dermatitis. Cats with the condition tend to lick, scratch or chew their skin compulsively so, if your pets seems preoccupied with his skin, it’s time to get to the source of the problem. Dermatitis is most commonly caused by allergies to fleas, but your pet may also be suffering inflammation due to environmental allergens or even his food. Flea allergy dermatitis occurs when pets have an adverse reaction to the saliva in flea bites and tends to occurduring the warmer months of the year, when pests are most active. Solving your cat’s skin condition can be as simple as solving his flea problem in these cases, so treat him with a veterinarian-prescribed flea medication. Even if you’re not sure your pet’s scratching is due to fleas, treat an itchy pet for them to rule out the problem. Remember, it can sometimes take months to fight a flea infestationand your pet’s skin problem can last just as long. Once you’ve ruled out fleas as the source behind Kitty’s constant itching, you’ll need to look at his diet. Food allergies are the second-most common cause of dermatitis in cats, and are due to an allergy to specific proteins in his food. Cats can develop food allergies at any point intheir lives, so it’s important to arrange a food allergy trial with your veterinarian even if your pet has eaten the same diet for years. By trying a special prescription diet—and nothing else, including treats—you can see whether your pet’s skin improves and, therefore, whether his dermatitis is caused by food. If his condition improves, you can work with your veterinarian to continue this special diet and control Kitty’s allergies. After ruling out both fleas and food as the culprit behind your pet’s inflamed skin, you can assume his dermatitis is caused by environmental allergens such as pollen or mold. This type of allergy is much harder to diagnose and manage, but your veterinarian can prescribe medication such as steroids or antihistamines to control Kitty’s chronic condition. Because cats with dermatitis tend to scratch, lick or chew on their skin, which can cause lesions that may become infected, it’s crucial to get to the bottom of your pet’s condition and treat him for dermatitis, whatever the root source.

What are the side effects of Simparica?

 by ben on 03 Jun 2019 |
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We all want to protect our pets from fleas, ticks and the diseases they carry, but some treatments can come with nasty side effects. Every good pet parent wants to keep fleas off his dog, but many worries about the side effects that can accompany various flea and tick treatments. Fortunately for conscientious dog moms and dads, Simparica offers a once-a-month chewable treatment that is FDA-approved and safe for Fido, taking the guesswork out of fighting fleas and ticks. Like other oral treatments, Simparicaworks by entering a dog’s bloodstream immediately after ingestion. When fleas or ticks bite, they are exposed to its FDA-approved ingredient sarolaner, the insecticide, and acaricide that kills parasites fast. Sarolanerstarts fighting fleas within three hours and begins to kill ticks after 8 hours—including the lone star tick, black-legged tick, brown dog tick, American dog tick, and Gulf Coast tick. Because this ingredient works differently on invertebrates than mammals, however, Simparica for dogs has been proven safe during field trials. Simparicaworks by impacting the nervous system of invertebrates such as fleas and ticks. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. GAGA-gated channels help to calm nerve transmissions, which sarolaner alters, creating an influx of nerve transmissions. At the same time, it opens glutamate-gated channels, which adds to the flood of nerve communications. The results are fatal for fleas and ticks but safe for mammals such as your dog. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrhea—both symptoms related to Fido’s digestive tract, rather than his nervous system. In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. Simparica is available by prescription only, so discuss any history your dog has of seizure disorders with your veterinarian when determining the best flea and tick treatment for your pet. In addition to killing fleas and several kinds of ticks, Simparicais effective in preventing and treating mange and ear mites. Thanks to its innovative formula, the treatment continues to work for 35 days, providing long-lasting relief from parasites and the diseases they carry. Simparica is available in different doses for dogs 2.8 pounds and over, but has not been evaluated for use in pregnant, breeding or nursing pets. Discuss Simparica chewable treats with your veterinarian when looking for a safe, effective way to arm your dog against biting parasites and the diseases they carry.
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