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Common brand names

Single ingredient

Combined ingredients

Generic products are available.

Uses of Ivermectin

Ivermectin is a broad-spectrum antiparasitic, predominantly used for heartworm prevention in dogs and cats.

For dogs: Used to prevent canine heart disease by eliminating heartworm larvae (Dirofilariaimmitis). Combined with Pyrantel to treat hookworm and roundworm.

For cats: Used to prevent feline heart disease by eliminating heartworm larvae, and for the removal and control of adult and immature hookworms (Ancylostomatubaeforme and A. braziliense).

Method of application

Oral application supplied as chewables or tablets. Application of generic products may differ.

Dosage and administration

Ivermectin is administered once a month with a dosage based on the animal’s body weight. It is important to weigh your pet first and use the correct product for your animal as noted on the packaging or recommended by your vet.

Chewables may be offered by hand or broken up and added to a small amount of food. If given by hand, the dog or cat should be encouraged to chew, rather than swallow the chewable whole.

Ivermectin is successful in preventing the development of heartworm for a month following the animal’s exposure to mosquitos. If administering seasonally, the first dose should be administered within 30 days of first exposure, and the last dose given within 30 days of the last exposure. It is important to administer Ivermectin on the same day each month to ensure maximum efficacy.

Note that approved doses may vary from country to country and you should always follow packaging directions.

Possible side effects

Rare adverse reactions reported in dogs treated with Ivermectin include depression/lethargy, vomiting, anorexia, diarrhea, mydriasis, ataxia, staggering, convulsions, and hypersalivation.

Dogs may experience mild hypersensitivity including diarrhea after treatment with Ivermectin, presumed to be a result of dead or dying microfilariae.

Reported side effects for cats include vomiting and diarrhea.

Side effects of products with combined ingredients (Ivermectin, Pyrantel) may differ.


Animals should be tested and cleared for existing heartworm before starting preventative treatment, as Ivermectin is not effective against adult heartworm.

Use with caution in collies or related breeds as these dogs have an increased sensitivity to the effect of Ivermectin, and toxicity can occur.

Not recommended for use with cats or dogs under 6 weeks of age.

Ivermectin has been tested as safe for use with pregnant or nursing dogs and cats.

Signs of toxicity

The following symptoms may indicate an overdose or sensitivity. Contact your veterinarian if you notice any of these signs or suspect your dog or cat has had an overdose.

Dogs: dilated pupils, staggering, drooling, vomiting, blindness, tremors, seizures, coma.

Cats: dilated pupils, diarrhea, loss of appetite, lack of reflexes, staggering, drooling, vomiting, blindness, tremors, seizures, coma, posterior paralysis.

Treatment of Ivermectin toxicity consists of supportive and symptomatic measures, with most pets recovering in 7-10 days.


Store at controlled room temperature of 59°-86°F (15°-30°C). Protect product from light.


This information is provided for general reference only and is not intended to replace the packaging label or veterinary advice. Always consult your veterinarian to ensure the supplied information applies to your specific pet. This page may not include all side effects, uses, brand names or applications.


Ivermectin drug information sheet
Ivermectin Information Sheet

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